STEM-SAFE - Translating a Multi-Organ NAM into an Industrial Standard for Safety Assessment of Hematopoietic Stem Cell-Based Gene Therapies
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Contract Description
Gene therapies (GTs) based on hematopoietic stem and progenitor cells (HSPCs) hold great promise, but their tumorigenicity risk, already observed in patients, is a significant concern. Current safety tests rely on oversimplified in vitro systems, often based on murine cells...